Reframing Global Variation in Heart Failure Trials
نویسندگان
چکیده
منابع مشابه
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46. Berkman LF, Blumenthal J, Burg M, et al; Enhancing Recovery in Coronary Heart Disease Patients Investigators (ENRICHD). Effects of treating depression and low perceived social support on clinical events after myocardial infarction: the Enhancing Recovery in Coronary Heart Disease Patients (ENRICHD) Randomized Trial. JAMA. 2003;289(23):3106-3116. 47. Freedland KE, Skala JA, Carney RM, et al....
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Randomized trials that affect regulatory approval, guideline, and third party payer considerations in patients with cardiovascular disease have increasingly required a relatively large number of patients and reliance upon geographic locations around the world. The reasons for inclusion of geographic locations around the world in these large-scale studies varies but, in general, these are relate...
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Hospitalization for acute heart failure (AHF) is a major public health problem, with 1 million hospitalizations annually in the United States.1 The development of new therapies for patients with AHF remains a significant challenge.2 One aspect of clinical trial design in AHF that has been particularly vexing is the choice of appropriate end points, a topic that has recently been reviewed in det...
متن کاملA global rank end point for clinical trials in acute heart failure.
Hospitalization for acute heart failure (AHF) is a major public health problem, with 1 million hospitalizations annually in the United States.1 The development of new therapies for patients with AHF remains a significant challenge.2 One aspect of clinical trial design in AHF that has been particularly vexing is the choice of appropriate end points, a topic that has recently been reviewed in det...
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OBJECTIVES This study was done to determine whether seasonal variation exists in hospitalizations and deaths due to heart failure (HF) and to examine possible contributors to such variability. BACKGROUND Although seasonal variation in the incidence of acute myocardial infarction and sudden death is well recognized, it is less well documented in HF. METHODS We used the linked Scottish Morbid...
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ژورنال
عنوان ژورنال: JACC: Heart Failure
سال: 2019
ISSN: 2213-1779
DOI: 10.1016/j.jchf.2018.12.012